Associate Professor · Pharmaceutical Chemistry

Dr. N. Kiruthiga

KMCH College of Pharmacy, Coimbatore – 641048, Tamil Nadu, India

Pioneering |
0
Publications
Scopus / WoS / PubMed
0
Patents
India · UK · Germany
0+
Years Experience
Teaching & Research
0
Books
2 Published · 1 Forthcoming
0+
Students Mentored
UG & PG Projects
0
Q1/Q2 Papers
Published 2025–2026

About Dr. Kiruthiga

Associate Professor of Pharmaceutical Chemistry with over 18.5 years of teaching experience and a sustained, fast-growing research record in computer-aided drug design and medicinal chemistry.

Research core centers on the design, synthesis and computational-to-experimental evaluation of flavonoid, chromone, pyrazoline and heterocyclic scaffolds against diabetes, inflammation, infection and cancer targets, with current work extending into HDAC-inhibitor design, machine-learning-assisted drug discovery, and marine bioactive compounds.

Author of 41 peer-reviewed publications (predominantly Scopus/Web of Science/PubMed-indexed, including 18 in Q1/Q2 journals since 2025), 6 patents, 3 authored/edited books and 4 book chapters, alongside a strong record of UG/PG mentorship, NBA/NAAC accreditation leadership, and peer review for Elsevier, Springer and Bentham Science journals.

NBA Criterion 1 Coordinator
Nominated PCI Inspector
Ph.D. Advisory Committee Member, VMRF
Reviewer: Elsevier, Springer, Bentham Science

Vision

To advance drug discovery through computational and medicinal chemistry, and to build institutional research strength through funded research, scholarly output, and academic excellence.

Mission

  • Secure extramural grants (DST, ICMR, AICTE, BIRAC, TNSCST)
  • Mentor UG/PG/PhD scholars toward publication-ready, patentable research
  • Elevate institutional accreditation standing through outcome-based education

Core Research Areas

Computer-Aided Drug Design

Molecular docking, MD simulation, virtual screening, QSAR modelling and computational toxicology using Maestro, AutoDock & BIOVIA Discovery Studio.

Molecular DockingMD SimulationQSAR

Medicinal Chemistry

Design and synthesis of flavonoid, chromone, pyrazoline and heterocyclic scaffolds with spectroscopic characterization (NMR, IR, Mass).

FlavonoidsChromonesPyrazolines

Drug Discovery

In-silico, in-vitro and in-vivo pharmacological screening for anti-diabetic, anti-inflammatory, antimicrobial and anticancer targets.

Anti-diabeticAnticancerAnti-inflammatory

HDAC Inhibitor Design

Design and synthesis of HDAC inhibitors for apoptosis induction in human cervical cancer cells, including piperidine hydroxamate scaffolds.

HDACApoptosisCancer

AI & Machine Learning

Machine learning and explainable AI applications in cheminformatics and drug discovery; Python-based tools for molecular fingerprint visualization.

Explainable AICheminformaticsPython

Marine Bioactive Compounds

Marine bioactive molecules as antiviral (HMPV, Nipah, Zika) and antimicrobial agents with focus on natural product drug discovery.

AntiviralMarine Natural ProductsHMPV

Spectroscopic Analysis

Structure elucidation and characterization using Nuclear Magnetic Resonance (NMR), Infrared (IR) spectroscopy, and Mass spectrometry.

NMRIR SpectroscopyMass Spec

Selected Publications

41 peer-reviewed publications (2007–2026) · Scopus / WoS / PubMed indexed · Impact factors up to 4.7

Showing 12 selected high-impact publications. 17 Q1/Q2 papers published in 2025–2026 alone.
2026
Flavonoid derivatives as anticancer agents
Yuan Chen, Xiaohua Tang, Yurong Zou, Dongwei Zhu, Selvaraj Muthusamy, Natarajan Kiruthiga, Panneerselvam Theivendren et al.
International Journal · Anticancer Research
Q1
2026
Plant-Derived Heterocyclic Compounds: A Promising Review on Natural Scaffolds
Jindong Dai, Xue Xia, Xincheng Hu, Thangamani Kanagaraj, Kanagaraj Rajalakshmi, Natarajan Kiruthiga, Dongwei Zhu et al.
Natural Products Review
Q1
2026
Design, synthesis, and evaluation of novel therapeutic scaffolds
Wanhui Dai, Dongwei Zhu, Kanagaraj Rajalakshmi, Sudhakar Pachiappan, Natarajan Kiruthiga, Panneerselvam Theivendren et al.
Medicinal Chemistry Communications
Q2
2026
Strategic Applications of Heterocyclic Compounds in Pharmaceutical Innovation
Kanagaraj Rajalakshmi, Yan Dong, Jindong Dai, Yuerong Zou, Natarajan Kiruthiga, P Balaji, Dongwei Zhu
Pharmaceutical Innovation Reviews
Q2
2026
Novel anti-inflammatory heterocyclic compounds
Panneerselvam Theivendren, Surabhi Panneerselvam, Jayakumari Swaminathan, Vijayakumar Murugesan, Natarajan Kiruthiga* et al.
European Journal of Medicinal Chemistry
Q1
2026
Marine bioactive molecules as antiviral agents
Stalin Arulsamy, Praveen Jambulingam Mani, Sivakumar Ravi, Kiruthiga Natarajan, Suresh Kumar Krishnan et al.
Marine Drugs & Natural Products
Q2
2026
Targeted anticancer potential of novel compounds
Jianxing Xu, Dongwei Zhu, Natarajan Kiruthiga, Kanagaraj Rajalakshmi, Panneerselvam Theivendren, Selvaraj Muthusamy et al.
Cancer Letters & Therapy
Q1
2026
Design and Synthesis of Piperidine Hydroxamate HDAC Inhibitors
Kiruthiga Natarajan*, SureshKumar Krishnan, Stalin Arulsamy, Adhirajan Natarajan, Venkatesh Gunasekar, Vaishnavi Vallinayagam
Journal of Medicinal Chemistry · HDAC/Apoptosis
Corresponding
2025
Development of Nipah virus drugs from FDA-approved drugs: An In-silico Approach
Panneerselvam Theivendran, Selvaraj Kunjiappan, Parasuraman Pavadai, Natarajan Kiruthiga, Anusuya Murugavel, Avinash Dayalan
Antiviral Research
Q1
2025
Exploring alkaloid-based scaffolds for drug design
Yumei Chen, Denghua Yu, Dongwei Zhu, Selvaraj Muthusamy, Natarajan Kiruthiga, Panneerselvam Theivendren, Kanagaraj Rajalakshmi et al.
Natural Products & Medicinal Chemistry
Q2
2025
Marine bioactive molecules as potential antiviral agents against HMPV
Stalin Arulsamy, Mohankumar Ramar, Suresh Kumar Krishnan, Kartiga Natarajan, Kiruthiga Natarajan*, Parasuraman Pavadai
Marine Pharmacology
Corresponding
2025
Emerging therapeutic targets in pharmaceutical research
Panneerselvam Theivendren, Parasuraman Pavadai, Selvaraj Kunjiappan, Natarajan Kiruthiga, Kumarappan Chidambaram et al.
Drug Discovery Today
Q1

Patents & Innovations

India
Patent #1

Synthesis of 4-methyl-2-((2-(2-nitrophenyl)-1-phenylvinyl)sulfonyl)thiophene

Novel synthesis methodology for sulfonyl-thiophene derivatives. Co-inventors: Dr. Panneerselvam Theivendren, Dr. T.R. Yoithapprabhunath, Dr. N. Kiruthiga et al.

Indian Patent
United Kingdom
Patent #2

Novel Pharmaceutical Composition

Co-inventors: Dr. Adarsh Sahu, Jyotika Mishra, Rituparna Palit, Dr. Natarajan Kiruthiga, Dr. Ravinesh Mishra et al.

UK Design Patent
Germany
Patent #3

Novel Pharmaceutical Formulation — German Design Patent

Co-inventors: Alagiri Abarnadevika, Anbazhagan, Dinesh Raja, Natarajan Kiruthiga, Premanandan Sruthi et al.

German Patent
India
Patent #4

Drug Interaction Analysis Compound

Co-inventors: Dr. R. Suthakaran, Dr. Teelavath Mangilal, Dr. S. Anand Reddy, Dr. N. Kiruthiga, Harish Kumar, Dr. Vivek Kumar

Indian Patent
India
Patent #5

Synthesis of N-(3-(1-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-(substituted) derivatives

Co-inventors: T. Sivakumar, N. Kiruthiga, T. Prabha, C. Selvinthanuja, E. Manickavalli et al.

Indian Patent
India
Patent #6

Synthesis of 7-substituted benzylidene-3-imino-2-phenyl-1-thioxo-hexahydropyrrolo pyrimidine derivatives

Co-inventors: N. Kiruthiga, C. Selvinthanuja, T. Prabha, T. Sivakumar

Indian Patent

Books & Book Chapters

Published

Text book of Intellectual Property Rights

Rubicon Publications, Edition 1

Dr. S. Muthukumar, Dr. N. Kiruthiga, Dr. R. Gayathri, Dr. C. Sundaramoorthi, Dr. A. Dinesh Raja, B. Kamaleshwari

Published · 2024

DRUG DOSSIER – VOL-1

South Asian Academic Publications, 2024

Dr. N. Kiruthiga, Dr. G. Saravanan, Dr. K. Suresh Kumar

ISBN: 978-93-92153-09-9

Forthcoming

Next-Generation Translational Medicine: Integrating AI, Systems Biology and Clinical Science

Academic Press (Edited Volume)

Editor: Dr. N. Kiruthiga, Dr. Saravanan Govindaraj, Dr. Dinesh Babu, Dr. Asha Josey, Dr. Gayathri Rajaram

Book Chapters (4)

01
Advancements In Cancer Treatment: Comprehensive Overview of Drug Delivery Methods
IIP Series, Volume 3, Book 4, Part 5, Chapter 5 · 2024
02
Pharmacokinetic and Pharmacodynamic Application to Peptides and Proteins in Drug Delivery
IIP Series, Volume 3, Book 4, Part 6, Chapter 6 · 2024
03
Success Stories: Impactful Applications of Cancer Biomarkers
Elsevier Academic Press
04
Immunity to Immunotherapy in Cancer
Academic Press · Cancer Immunotherapy: Pros, Cons, and Beyond (Chapter 14)

Professional Experience

March 2022 – Present Current
Associate Professor
KMCH College of Pharmacy, Coimbatore – 641048
  • Design, synthesis and evaluation of novel therapeutic moieties for pharmacological importance
  • Deliver medicinal and organic chemistry curriculum across B.Pharm, Pharm D and M.Pharm programs
  • Mentor UG/PG research scholars; NBA Criterion 1 Coordinator
February 2011 – February 2022 11 years
Associate Professor
Nandha College of Pharmacy, Erode
  • Led department research output — organized 18+ national/international conferences and FDPs
  • Drafted and applied for TNSCST and BIRAC research funding
  • Established Value Added Program framework (6 courses)
December 2007 – October 2009
Assistant Professor
Erode College of Pharmacy, Erode
September 2006 – October 2007
Lecturer
JKK Natarajah College of Pharmacy, Komarapalayam, Namakkal District

Education & Qualifications

Ph.D.
2014 – 2021

Ph.D., Pharmaceutical Chemistry

The Tamil Nadu Dr. MGR Medical University, Guindy, Chennai

Thesis: Design, Synthesis and Characterization of Lead Flavonoid Analogues and Evaluation of their Biodynamic Properties

M.Pharm
2004 – 2006

M.Pharm, Pharmaceutical Chemistry

JKK Natarajah College of Pharmacy, Komarapalayam, Namakkal District

Thesis: Phytochemical analysis of petroleum and methanolic extract of Scutia myrtina and anti-inflammatory / anti-microbial activity evaluation

B.Pharm
1999 – 2003

B.Pharm

Annai JKK Munirajah College of Pharmacy and Research Foundation, Komarapalayam, Namakkal District

Dissertation: Diabetic Foot Ulcer — A Review

Key Skills

Research & Technical

Molecular Docking Molecular Dynamics Simulation Virtual Screening QSAR Modelling Python / AI-ML Maestro (Schrödinger) AutoDock BIOVIA Discovery Studio Organic Synthesis NMR / IR / Mass Spectroscopy GraphPad Prism GraphPad InStat ChemDraw ChemSketch Computational Toxicology

Academic & Leadership

Curriculum Design Research Mentorship Grant Writing (DST/ICMR/BIRAC) NBA/NAAC Accreditation ISO 21001 Integration Peer Review (Elsevier/Springer) Question Paper Setting B.Pharm · Pharm D · M.Pharm Teaching Outcome-Based Education Event Coordination

Leadership & Contributions

NBA Criterion 1 Coordinator

Led outcome-based accreditation strategy for National Board of Accreditation criteria, strengthening institutional competitive positioning.

PCI Inspector (Nominated)

Nominated by the Pharmacy Council of India to serve as Inspector for pharmacy institution evaluations per council regulations.

Ph.D. Advisory Committee Member

External Member, Ph.D. Research Advisory Committee, Vinayaka Mission's Research Foundation (Deemed University), Salem — February 2026 to present.

Institution Innovation Council

Active member organizing Entrepreneurship and YUKTHI activities; promotes research-to-innovation translation among students.

Value Added Program Coordinator

Coordinated 6 intensive courses: First Aid, Fire Safety, Scientific Writing, Data Integrity, Mental Health & Physical Safety, Life Skills Management.

18 Conferences & FDPs Organized

Led organization of 18 National/International Conferences, Seminars, Faculty Development Programmes, and Webinars including AICTE-sponsored events.

Evaluator & External Committee Roles

International Conference Evaluator — AIMST International Conference on Health Science and Technology (AICHST 2023), AIMST University, Kedah, Malaysia · 24 Nov 2023
International Conference Evaluator — 1st International Joint Conference on Medical & Health Sciences (IJCMHS 2024), VISTAS–UCMI · 23–24 Jul 2024
External Ph.D. Advisory Committee Member — Vinayaka Mission's Research Foundation (Deemed University), Salem · February 2026 to Present

Contact Dr. Kiruthiga

Location Coimbatore, Tamil Nadu, India
(Open to relocating to Chennai)
Google Scholar View Publications Profile
KMCH College of Pharmacy
Coimbatore – 641048, Tamil Nadu, India
Department of Pharmaceutical Chemistry

KMCH College of Pharmacy is a premier pharmacy institution in Coimbatore, offering B.Pharm, Pharm D, and M.Pharm programs with a strong emphasis on research and innovation.

PCI Approved NBA Accredited AICTE Approved